2018 REU Student Profile
Rachel studies chemistry at the Xavier Univeristy in Cincinnati Ohio. This summer she is working with Professor Ross' and her research team.
Carbon nanotube fiber electrodes for enhanced melatonin detection
The goal of my research project is to develop and characterize sensors for melatonin detection. This project involves fabricating carbon-fiber microelectrodes and using fast-scan cyclic voltammetry, which is an electrochemical technique. In addition, I am making a buffer solution of physiological pH, and stock solutions of three neurotransmitters found in the body: dopamine, melatonin, and serotonin. The carbon-fiber electrodes I am making in the lab exhibit fouling (reduced electrode sensitivity) for melatonin and serotonin in the traditional voltage wave form, but literature has shown that carbon nanotube (CNT)-fibers reduce the extent of fouling. I will obtain the CNT-fibers from Dr. Alvarez’s lab, and compare the fouling and surface properties of the carbon-fiber microelectrodes and CNT-fibers. This will be done through observing the current vs. time graphs as fouling occurs. In addition, I will analyze the surfaces of the electrodes to see the difference in appearance of fouled and non-fouled electrodes. Eventually, these novel techniques with CNT-fibers can be used to clearly view melatonin and dopamine activity simultaneously, and understand how these neurotransmitters interact in the body.
- Rachel Krevh
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