Updated: Nov 28, 2018
2018 REU Student Profile
Rachel studies chemistry at the Xavier Univeristy in Cincinnati Ohio. This summer she is working with Professor Ross' and her research team.
Carbon nanotube fiber electrodes for enhanced melatonin detection
The goal of my research project is to develop and characterize sensors for melatonin detection. This project involves fabricating carbon-fiber microelectrodes and using fast-scan cyclic voltammetry, which is an electrochemical technique. In addition, I am making a buffer solution of physiological pH, and stock solutions of three neurotransmitters found in the body: dopamine, melatonin, and serotonin. The carbon-fiber electrodes I am making in the lab exhibit fouling (reduced electrode sensitivity) for melatonin and serotonin in the traditional voltage wave form, but literature has shown that carbon nanotube (CNT)-fibers reduce the extent of fouling. I will obtain the CNT-fibers from Dr. Alvarez’s lab, and compare the fouling and surface properties of the carbon-fiber microelectrodes and CNT-fibers. This will be done through observing the current vs. time graphs as fouling occurs. In addition, I will analyze the surfaces of the electrodes to see the difference in appearance of fouled and non-fouled electrodes. Eventually, these novel techniques with CNT-fibers can be used to clearly view melatonin and dopamine activity simultaneously, and understand how these neurotransmitters interact in the body.
- Rachel Krevh
Updated: Nov 28, 2018
2018 REU Student Profile
George studies biochemistry at Taylor University. This summer he is learning more about biochemistry by conduction research with Professor Merino's research team.
I have the privilege of being a part of Dr. Merino’s research group. The goal of the research is to develop a new sunscreen that works by controlling the levels of reactive oxygen species (ROS) within the cell. The hope is to be able to prevent melanoma development as cancerous cells require a higher concentration of ROS to grow and survive. My part in Dr. Merino’s research group deals with the use and treatment of fibroblasts. I will be culturing human cells for the use in various tests. These cells will be tested after treatment with hydrogen peroxide or ultraviolet light to test the apocynin compound created by another group member. I will be testing apocynin’s ability to decrease the ROS concentration within the cells. I will perform MTT assays and tests with Dichlorofluorescein treatment to be able to quantify our results.
- George Gray
Updated: Jun 20, 2018
Jocelyn Brown, Osar Otasowie, Amani Gaddy, Kyrus Tsai, Ariana McDarby, Joseph Holbrook, Rachel Krevh, Matthew Hecker, Jerrica Brown, George Grey, Sydney White, Ethan Quinn